Friday, May 22, 2020
The Impact Of Television On Mass Media - 2006 Words
The Impact Television has on Mass Media The invention of the television affected mass media as a whole, as they now see the news, weather, and entertainment through a motion picture screen as compared to just hearing it from the original radio. With the help of inventors and newly evolving technology, the television has become a part of American households. Beyond televisions effects on family life and habits, the new medium had wide-ranging effects on society, including commercial and economic impact. The invention of the radio was a revolutionary invention that helped the television become a reality. With help of many inventors and scientists, the radio was in the process of the making in the early 1800s. German scientist Heinrich Hertz proved the existence of radio waves, where signals were sent by the waves instead of wire. The radio changes sound or signals into radio waves that travel through air, space and solid objects, which then turn back into sound, words, or music when returned to the receiver (ââ¬Å"Television Invention Timelineâ⬠). In 1895, Gugliemo Marconi invented the wireless telegraph where he used radio waves to transmit Morse code. By 1906, Marconi shared the Nobel Prize for physics with Ferdinand Braun in recognition of contributions to the development of wireless telegraphy (ââ¬Å"Television Invention Timelineâ⬠). In 1920, over 500 stations were broadcasting news; music, sports, drama, variety shows, and by 1930 most households in the U.S and Europ e had at leastShow MoreRelatedHistory of Mass Media1150 Words à |à 5 PagesHISTORY OF MASS MEDIA UNIT PLAN LECTURE AND TUTORIAL:- DAY : MONDAY TIME : 8.00 to 11.00 am ROOM : R4.2 OBJECTIVE To introduce students to the historical development of media, including books, newspapers, magazines, radio and TV broadcasting and cinema. Students will be able to trace the emergence of modern media institutions from their historical roots and discuss the impact of social and technological change. This will be ableRead MoreMedia Influence Mass Media795 Words à |à 4 PagesMass Media and the Influence on America and Television By. Mozelle Jones HUMANITIES In real life, we are in Mass Media and we did not even know it. Everything from you learning to just leisure involvement. The cultural products that influence mass media and has taking part is Net Flix. It has made an impact on the movie business where television can be used to see movies and mass media. Television still has an impact on cultural meanings. It shows us the news, ads, and movies that changeRead MoreMass Media and the Vietnam War Essay842 Words à |à 4 PagesMass Media and the Vietnam War Many people at the beginning and before the Vietnam War were in confusion on whether going to war was such a good thing; this mainly consisted of the American public. By the time it had reached the peak of the war much of the American public had swung towards being for the war. This was mainly due the mass media at the time, one integral part of the mass media that often swayed public opinion was television, it proved to be such an effectiveRead MoreThe Impact Of Mass Media On Youth And Society1378 Words à |à 6 PagesThe Impact of Mass Media on the Youth and Society Nowadays, the issue of mass media has caused much debate in the modern society, as well as mass media is becoming more important as a component that negatively affects the behavior of young people. There are many other factors, such as micro-environment, economic instability, the decline of moral values affecting children and young people and encourage them to commit unlawful acts. However, unlimited access to the Internet, mobile phone use in theRead MoreThe Media And Its Impact On Society Essay1721 Words à |à 7 Pagesonce said, ââ¬Å"Whoever controls the media, controls the mindâ⬠. The Media have becoming one of the most dominant source of education of the 21st century. We could argue that most americans use the media as their main source of information. The side effect on that is the fact that the media is very polarized. With the ongoing polarization, we could hypothesize that people would have been more politically educated and oriented if the media was not infiltrated. Mass media is expected to be educational. PublicRead MoreThe Media And Its Impact On Society Essay1723 Words à |à 7 Pagesonce said, ââ¬Å"Whoever controls the media, controls the mindâ⬠. The Media have become one of the most dominant source of education of the 21st century. We could argue that most Americans use the media as their main source of information. The side effect of that is the fact that the media are very polarized. With the ongoing polarization, we could hypothesize that people would have been more politically educated and oriented if the media was not infiltrated. Mass media are expected to be educational.Read MoreCulture and the Mass Media1400 Words à |à 6 PagesImpact of Mass Media on Enculturation The mass media and culture go hand and hand in today s society. The American culture thrives on the Mass media and this has become American culture today. ââ¬Å"Mass media is any medium used to transmit mass communication. Until recently mass media was clearly defined and was comprised of the eight mass media industries; books, newspapers, magazines, recordings, radio, movies, television and the Internet (Lane, 2007).â⬠The mas media is no longer simple to defineRead MoreMass Media and Popular Culture953 Words à |à 4 PagesMass Media and Popular Culture March, 2009 Let us face the facts, mass media and popular culture need each other to coexist. Furthermore, in todays society the mass media serves the interest of popular culture. Moreover, it is the vehicle of free speech in a diverse, multicultural society. In addition, mass media refers to communication via radio, televisions, movie theaters, television, newspapers, magazines, and, etc; thereby, reaching out to the larger audience. On the contrary, popularRead MoreMass Media And Its Impact On Society1306 Words à |à 6 Pagesis mass media. Mass media is a means of communication that reach number of people in a short time. Mass media includes television, newspaper, magazine, radio and Internet (Nariman,2011) . It is a large pool of information from where every type of information can be extracted and is widening more and more. Mass media influences the society especially the younger generation and shape their opinions and decisions. The study of the impacts of mass media requires a great understanding. Mass media haveRead MoreEssay about Mass Media and Popular Culture1491 Words à |à 6 PagesMass Media and Popular Culture: Effects on the Population Mass Media and Popular Culture Mass media and popular culture go hand in hand. This paper will discuss the impact of mass media on enculturation, examine the relationships among media, advertising and the formation of normative cultural values, and discuss the impact of the internet on popular culture and the way we communicate today. Real world examples of this impact will be provided to prove our point of view and the overall effect
Wednesday, May 6, 2020
The Death Of A Classical Music - 1181 Words
Know once you have adopted these three roles, there is another all I would like you to assume, this I think just paints the whole picture, this is sort of the background canvas of which you paint the rest of this portrait. You need to understand something the parents these days have long since forgot, and are going to have to relearn again your grandparents knew this, but todayââ¬â¢s generation appearance doesnââ¬â¢t seem to, and that is you do not get to design your children, nature would never have permitted that to, evolution would not have allowed a generation of a species to be so influenced by the previous generation, it hasnââ¬â¢t happened and it doesnââ¬â¢t happen, and it especially doesnââ¬â¢t happen in children, you do not design your children, andâ⬠¦show more contentâ⬠¦What, we learned in the last 20 years, of research in neuroimaging, behaviour genetics, developmental psychology, neuropathology can be boiled down to this phrase, your child is born w ith more than 400 psychological traits, that will emerge as they mature, and they have nothing to do with you. So the idea that you are going to engineer personalities, and IQ and academic achievement skills and all these other things, just isnââ¬â¢t true. Your child is not a blank slate and which you get to write, if you would like to read more about this please read, ââ¬Å"the blank slateâ⬠, which is a review of all of this information for parents and why it isnââ¬â¢t true. The better of you is it your child is a genetic mosaic of your extended family, which means this is a unique combination of the traits that run in your family line. I like the Shepherd view, you are a shepherd, you donââ¬â¢t design sheep, the engineering of you make surely responsible for and for everything, everything that goes right and everything that goes wrong. This is my parents come to us with such guilt, more guilt EV than we have ever seen in previous generations. Because parents today b elieve that all about them and what they do, in if they donââ¬â¢t get it right if a child has a disability theyââ¬â¢ve done something wrong.When in fact the opposite is true. This is nothing to do with your particular brand of
Profit Maximization Model Free Essays
SAMPLE ANSWER FOR QUESTION 5 Profit-making is one of the most traditional, basic and major objectives of a firm. Profit-motive is the driving-force behind all business activities of a company. It is the primary measure of success or failure of a firm in the market. We will write a custom essay sample on Profit Maximization Model or any similar topic only for you Order Now Profit earning capacity indicates the position, performance and status of a firm in the market. In spite of several changes and development of several alternative objectives, profit maximization has remained as one of the single most important objectives of the firm even today. Both small and large firms consistently make an attempt to maximize their profit by adopting novel techniques in business. Specific efforts have been made to maximize output and minimize production and other operating costs. Cost reduction, cost cutting and cost minimization has become the slogan of a modern firm. It is a very simple and unambiguous model. It is the single most ideal model that can explain the normal behavior of a firm. Main propositions of the profit-maximization model The model is based on the assumption that each firm seeks to maximize its profit given certain technical and market constraints. The following are the main propositions of the model. 1. A firm is a producing unit and as such it converts various inputs into outputs of higher value under a given technique of production. 2. The basic objective of each firm is to earn maximum profit. 3. A firm operates under a given market condition. 4. A firm will select that alternative course of action which helps to maximize consistent profits 5. A firm makes an attempt to change its prices, input and output quantity to maximize its profit. The model Profit-maximization implies earning highest possible amount of profits during a given period of time. A firm has to generate largest amount of profits by building optimum productive capacity both in the short run and long run depending upon various internal and external factors and forces. There should be proper balance between short run and long run objectives. In the short run a firm is able to make only slight or minor adjustments in the production process as well as in business conditions. The plant capacity in the short run is fixed and as such, it can increase its production and sales by intensive utilization of existing plants and machineries, having over time work for the existing staff etc. Thus, in the short run, a firm has its own technical and managerial constraints. But in the long run, as there is plenty of time at the disposal of a firm, it can expand and add to the existing capacities build up new plants; employ additional workers etc to meet the rising demand in the market. Thus, in the long run, a firm will have adequate time and ample opportunity to make all kinds of adjustments and readjustments in production process and in its marketing strategies. It is to be noted with great care that a firm has to maximize its profits after taking in to consideration of various factors in to account. They are as follows ââ¬â 1. Pricing and business strategies of rival firms and its impact on the working of the given firm. 2. Aggressive sales promotion policies adopted by rival firms in the market. 3. Without inducing the workers to demand higher wages and salaries leading to rise in operation costs. 4. Without resorting to monopolistic and exploitative practices inviting government controls and takeovers. 5. Maintaining the quality of the product and services to the customers. 6. Taking various kinds of risks and uncertainties in the changing business environment. . Adopting a stable business policy. 8. Avoiding any sort of clash between short run and long run profits in the business policy and maintaining proper balance between them. 9. Maintaining its reputation, name, fame and image in the market. 10. Profit maximization is necessary in both perfect and imperfect markets. In a perfect market, a firm is a price-taker and under imperfect market it becomes a price-searcher. A ssumptions of the model The profit maximization model is based on tree important assumptions. They are as follows ââ¬â 1. Profit maximization is the main goal of the firm. 2. Rational behavior on the part of the firm to achieve its goal of profit maximization. 3. The firm is managed by owner-entrepreneur. Determination of profit ââ¬â maximizing price and output Profit maximization of a firm can be explained in two different ways. à ·Ã à à à à à à Total Revenue and Total Cost approach. à ·Ã à à à à à à Marginal Revenue and Marginal Cost approach. Profits of a firm are estimated by making comparison between total revenue and total costs. Profit is the difference between TR and TC. In other words, excess of revenue over costs is the profits. Profit = TR ââ¬â TC. If TR is equal to TC in that case, there will be break even point. If TR is less than TC, in that case, a firm will be incurring losses. In this case, we take in to account of total cost and total revenue of the firm while measuring profits. It is clear fromà the following diagram how profit arises when TR is greater than that of TC. 2. MR and MC approach In this case, we take in to account of revenue earned from one unit and cost incurred to produce only one unit of output. A firm will be maximizing its profits when MR= MC and MC curve cuts MR curve from below. If MC curve cuts MR curve from above either under perfect market or under imperfect market, no doubt MR equals MC but total output will not be maximized and hence total profits also will not be maximized. Hence, two conditions are necessary for profit maximization- 1. MR = MC. 2. MC curve cut MR curve from below. It is clear from the following diagrams. Justification for profit maximization 1. Basic objective of traditional economic theory. The traditional economic theory assumes that a firm is owned and managed by the entrepreneur himself and as such he always aims at maximum return on his capital invested in the business. Hence profit-maximization becomes the natural principle of a firm. 2. A firm is not a charitable institution. A firm is a business unit. It is organized on commercial principles. A firm is not a charitable institution. Hence, it has to earn reasonable amount of profits. 3. To predict most realistic price-output behavior. This model helps to predict usual and general behavior of business firms in the real world as it provides a practical guidance. It also helps in predicting the reasonable behavior of a firm with more accuracy. Thus, it is a very simple, plain, realistic, pragmatic and most useful hypothesis in forecasting price output behavior of a firm. 4. Necessary for survival. It is to be noted that the very existence and survival of a firm depends on its capacity to earn maximum profits. It is a time-honored hypothesis and there is common agreement among businessmen to make highest possible profits both in the short run and long run. 5. To achieve other objectives. In recent years several other objectives have become much more popular and all these objectives have become highly relevant in the context of modern business set up. But it is to be remembered that they can be achieved only when a firm is making maximum profits. Criticisms 1. Ambiguous term. The term profit maximization is ambiguous in nature. There is no clear cut explanation whether a firm has to maximize its net profit, total profit or the rate of profit in a business unit. Again maximum amount of profit cannot be precisely defined in quantitative terms. . It may not always be possible. Profit maximization, no doubt is the basic objective of a firm. But in the context of highly competitive business environment, always it may not be possible for a firm to achieve this objective. Other objectives like sales maximization, market share expansion, market leadership building its own image, name, fame and reputation, spending more time with members of the family, enjoying leisure, develo ping better and cordial relationship with employees and customers etc. lso has assumed greater significance in recent years. 3. Separation of ownership and management. In many cases, to-day we come across the business units are organized on partnership or joint stock company or cooperative basis. In case of many large organizations, ownership and management is clearly separated and they are run and managed by salaried managers who have their own self interests and as such always profit maximization may not become possible. 4. Difficulty in getting relevant information and data. In spite of revolution in the field of information technology, always it may not be possible to get adequate and relevant information to take right decisions in a highly fluctuating business scenario. Hence, profits may not be maximized. 5. Conflict in inter-departmental goals. A firm has several departments and sections headed by experts in their own fields. Each one of them will have its own independent goals and many a times there is possibility of clashes between the interests of different departments and as such always profits may not be maximized. 6. Changes in business environment. In the context of highly competitive and changing business environment and changes in consumerââ¬â¢s tastes and requirements, a firm may not be able to cope up with the expectations and adjust its policies and as such profits may not be maximized. 7. Growth of oligopolistic firms. In the context of globalization, growth of oligopoly firms has become so common through mergers, amalgamations and takeovers. Leading firms dominate the market and the small firms have to follow the policies of the leading firms. Hence, in many cases, there are limited chances for making maximum profits. 8. Significance of other managerial gains. Salaried managers have limited freedom in decision making process. Some of them are unable to forecast the right type of changes and meet the market challenges. They are more worried about their salaries, promotions, perquisites, security of jobs, and other types of benefits. They may lack strong motivations to make higher profits as profits would go to the organization. They may be contented with only satisfactory level of profits rather than maximum profits. 9. Emphasis on non-profit goals. Many organizations give more stress on non-profit goals. From the point of view of todayââ¬â¢s business environment, productivity, efficiency, better management, customer satisfaction, durability of products, higher quality of products and services etc. have gained importance to cope with business competition. Hence, emphasis has been shifted from profit maximization to other practical aspects. 10. Aversion to reduction in power. In case of several small business units, the owners do not want to share their powers with many new partners and hence, they try to keep maximum powers in their hands. In such cases, keeping more power becomes more important than profit maximization. 11. Official restrictions over profits of public utilities. Public utilities or public corporations are legally prohibited to make huge profits in many developing countries like India. Thus, it is clear that a firm cannot maximize its profits always. There are many constraints in the background of multiple objectives. Each one of the objectives has its own merits and demerits and a firm has to strike a balance between all kinds of objectives. How to cite Profit Maximization Model, Essay examples
Sunday, April 26, 2020
Measuring tools Essay Example
Measuring tools Essay Either the aim or objective and the type of quantitative approach was clearly stated within the abstract or summary of all the papers. Identification of the purpose and type of research at the beginning of the paper has several immediate advantages and limitations. From a nursing perspective, it is possible to determine if the research is relevant to patients in a particular care setting. However, as McCaughan (1999) points out, subtle differences may only be apparent with further exploration of the study. Secondly, clarity of purpose suggests a well-planned study that will deliver valid and useful data. Thompson (1999) concurs with this view and suggests that without a clear statement of aims the reader is unable to determine whether the research achieves its objectives or not. Furthermore, with unclear aims, there could be a tendency towards data-trawling, which may result in providing spurious results. Although I agree with the views of Thompson (1999) and McCaughan (1999), I believe there can be concerns with stating the type of method used in conducting the research. For instance, there could be a tendency to accept the design at face value or for it to bias the critical analysis of the study. Lais (1998), study is described as a prospective, nonrandomised study. According to Woods and Catanzario (1988), a prospective design aims to observe a sample on at least two occasions over a period of time, the aim being to reduce the likelihood of bias in reporting the relationship between the cause and effect. We will write a custom essay sample on Measuring tools specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Measuring tools specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Measuring tools specifically for you FOR ONLY $16.38 $13.9/page Hire Writer Whereas Lais (1998) study consisted of gathering information for a period of one month and could therefore be called prospective, it is not clear whether all the criteria for a true prospective design were applied or not. However, this is not to say that the research findings themselves would not be valid and reliable. Rather that even though there is a clear statement of the type of research, care must be taken that it does not influence personal judgement or the analysis of the study. Having determined that initially, the information given in the abstract of a study can have advantages and limitations, the next point will briefly consider the value of including or excluding a literature review within the study. LITERATURE REVIEW None of the studies reviewed in this assignment contained a literature review. However, there is some evidence that previous studies had been used to inform the investigations. Homer (1998) refers to previous studies within the methodology section and again in the discussion. The studies referred to are included in the reference list. Although the material in the reference list is relevant to the topic it only contains references for seven previous studies. Similarly, Lai (1998) cites previous studies within the discussion. Again the reference list only contains a few references. On the other hand, Curran et als (2000) study incorporates references to numerous previous work throughout the text. The value of including a literature review in a quantitative study is that it enables the research problem to be put into context or to identify gaps and weaknesses in prior studies so as to justify the current investigation. Also as Carnwell and Daly (2001) discuss it is valuable in demonstrating insight into the current state of knowledge within the relevant field. However, the exclusion of a literature review does not necessarily mean that the researchers did not undertake one. On the other hand, exclusion makes it difficult to determine the reason for undertaking the studies. For example, although, it appears that Lais (1998) study may have been carried out, at least in part, to support a cost saving initiative within his medical centre, none of the referenced material concerns this issue.Ã However, there is a common understanding throughout the studies regarding the nature of the topic being investigated. In particular, all of the papers acknowledge that peripheral venous cannulae are associated with the development of phlebitis. THEORETICAL/CONCEPTUAL FRAMEWORK Although none of papers (Curran et al 2000, Homer 1998, Lai 1998) identify a theoretical or conceptual framework that guided the research, there is allusion to the principles of some of the theories. For example, Curran (2000) discusses two causes of phlebitis, insertion site infection and physiochemical reactions. Similarly, Lai (1998) refers to infusion-related phlebitis and sepsis. On the other hand, Homer does not appear to refer to any theoretical framework in his study. In conclusion, it does not seem that theoretical models had a major influence on the studies. DEFINITIONS OF PHLEBITIS The studies have all identified phlebitis by using clinical indicators and severity rating scales. However, there does not appear to be common indicators or scales to identify the severity of phlebitis. For example, Lai (1998) has defined phlebitis as a palpable cord or at least two of the following, tenderness, warmth, erythema and induration. There is no particular reference as to the origin of the definition, although it appears to have been adapted from the inflammation scale used by the IV team within the hospital where the study took place. Similarly, the origin of the inflammation scale is not reported. According to Lais (1998) definition, phlebitis would be given a score of 3 or 4. Homer (1998) also defines phlebitis by clinical categorisation and allocating scores. However, the categories and scoring are different to those used by Lai (1998). Using Homers (1998) definition would give phlebitis a score between 2 and 4. Homers (1998) scale is not referenced but a significant difference from the one used by Lai (1998) is the exclusion of induration as a clinical indicator. Curran et al (2000) referred to the existing literature for indications of phlebitis. The eventual approach adopted contained two categories, erythema equal to or extending more than 3cm from the insertion site and/or purulent discharge with either or both being given a rating of 2 if present. Curran (2000) reports that this scale had been used in previous studies and includes references within the text, but does not offer any further information. However, there is no discussion as to any previous validation process that may have been used. As we have seen, phlebitis has been categorised and classified in different ways by different authors unique to their own study. Previous studies may have guided some of the categorisation. For example, Homer (1998) refers to the classification of phlebitis by Maki and Ringer (1991 cited in Homer 1998 p5) and Tager(1983 cited in Homer 1998 p5) but develops his own scale for classifying phlebitis. As a result, there appears to be no consensus of opinion regarding the rating and definition of phlebitis between the studies under review.Ã As well as impacting on the accuracy of assessing and identifying severity of phlebitis, the lack of a common assessment tool for defining and measuring phlebitis may impact on the generalisability of the research. Campbell (1998) suggests that the use of a uniform scale that measures the degree of phlebitis is also beneficial in providing criteria for standardising documentation. ACCURACY, VALIDITY AND RELIABILITY OF THE ASSESSMENT TOOL Each of the studies used clinical indicators and a rating scale to determine and measure the severity of phlebitis. The strength and appropriateness of this type of measuring tool has been demonstrated in other quantitative studies within the same field. (Dinley 1976, Maddox and Rush 1977, Baxter Healthcare Ltd. 1988 cited in Campbell 1998 p 1311) However, there are limitations and weaknesses with the tools used in the studies under review. None of the researchers have discussed how validity and reliability was assessed. Although both Lai (1998) and Homer (1998) have used tools that do not appear to have been used in previous situations, there is no report on a pilot study being carried out prior to the main study. Lais (1998) measurement tool has a number of limitations. Within the study Lai (1998) reports that the intravenous site was monitored according to a well-defined inflammation scale and has published the indicators and rating for the inflammation scale in the study. However, the tool that Lai used to obtain the data on phlebitis in his study was not the reported inflammation scale. Lai (1998) appears to have used elements of the inflammation scale and designed a scale that has some differences from the inflammation scale that he reported was used. The inflammation scale uses pain and swelling as clinical indicators but in the scale that was used in the study swelling has been excluded and pain has reduced to tenderness. Another point of concern is the implication that the severity of phlebitis could be measured on a scale designed to measure the presence and severity of inflammation. This may lead to confusion between rating phlebitis and inflammation. In other words, it is not certain that the tool actually used measured what it was supposed to measure. Homer (1998) referred to other studies before adopting a different set of clinical indicators in his scale that he reports as being more rigorous than Maki and Ringers (1991 cited in Homer 1998 p5) scale but less so than Tagers (1983 cited in Homer 1998 p5). However, there does not appear to be any reference to testing validity of the scale. A point of accuracy concerns the use of the scale for measuring infiltration as well as phlebitis. Although, the measuring of infiltration is not mentioned in the discussion section, the methods section gives the grading of infiltration as 1-3. The grading on the scale for phlebitis is 2-4. According to Homer (1998), the majority of the incidences of phlebitis were graded at 2. Consequently, phlebitis and infiltration were both graded as 2 using the same clinical indicators. Again, this raises the point of whether the scale measured what it was supposed to measure. The strength of Curran et als (2000) measurement tool lies in the fact that it had been used in other studies. However, there is no discussion as to the validity or reliability of the tool. It is also unclear as to whether Curran et al (2000) carried out a pilot study or not. There is a reference in the paper to collecting data on forty catheters, which is not the total number of the whole data collection. However, although analysis was carried out on the data collected from this, there is no further discussion. In summary, there appears to be serious weakness and limitations with the accuracy of the measuring tools. Validity and reliability appear not to have been tested. As McCaughan (1999) points out, if measuring tools are not valid then neither are study findings. Error due to the measuring technique used, the instrument itself or the person doing the measuring may affect reliability. Therefore, the next point will consider the issue of interrater reliability.
Thursday, March 19, 2020
Hydrophilic Matrix Tablets Essay Example
Hydrophilic Matrix Tablets Essay Example Hydrophilic Matrix Tablets Essay Hydrophilic Matrix Tablets Essay How Changes in the Formulation of Hydrophilic Matrix Tablets Effects Drug Release and Tablet Hydration Discussion: Part A ( hydration ) : Experiment A1: Experiment A1 was carried out to see how the belongingss of different polymers consequence the hydration of hydrophilic matrix tablets. Four different polymers were tested Sodium Alginate 100 % ( SA ) , Xanthan Gum 100 % ( XG ) , Hydroxypropylmethylcellulose 100 % ( HPMC ) and Methylcellulose 100 % ( MC ) . These were compared to a control which was a standard lactose tablet. They were all tested in fake stomachic fluid ( SGF ) and fake enteric fluid ( SIF ) individually. First if we compare all the matrix tablets to the milk sugar we can see that the lactose tablet wholly disintegrates with in the first 30mins in both fluids. However the matrix tablets barely disintegrate and are still present at 240mins. This is because the lactose tablet does non incorporate a polymer. Upon initial wetting of the matrix tablets the polymer begins to hydrate organizing a syrupy gel bed. In order for drug to be released it has to spread through this bed. This takes clip and this allows sustained dru g release. Whereas the lactose tablet merely disintegrates and releases all the drug straight off. Sodium alginate ( SA ) is a natural hydrophilic polyose and is a additive polymer. We can see from the consequences that it was quickly able to organize a gel bed nevertheless the size of the gel bed was different in the two fluids. SA formed a larger gel bed in the SGF than the SIF as it got to 4mm in the SGF and merely 2.5 in the SIF. It besides took longer for the gel to increase in size in the SIF. The nucleus breadth decreased as clip went on and were similar for both fluids but overall it was somewhat lower in the SGF at the clip points. The difference in the breadth of the gel bed between the two fluids shows that the hydration of SA is dependent on pH. SIF has a pH of around 7.2 so is impersonal nevertheless SGF has a pH of around 2 to 3 doing it acidic. As the concentration of H ions addition ( in acidic conditions ) there is inter-conversion of carboxylate anions ( sodium alginate ) to free carboxyl groups ( alginic acid ) . This means in acidic conditions like SGF SA is ab le to swell but is indissoluble nevertheless it is soluble in impersonal conditions. Therefore the gel bed may acquire dissolved in SIF and consequence in a lower breadth compared to SGF which would hold a thick gel bed. Hence alterations in pH are likely to change the hydration features of the polymer and consequence its action on sustained drug release. Xanthan gum ( XG ) , an anionic polymer, showed different hydration features compared to SA. It produced the widest gel bed the fastest at 30mins compared to the other polymers in both the fluids. This shows its ability to organize a thick gel bed rapidly. It was besides able to bring forth the widest gel bed in the SIF compared to the other tablets. It had similar features in both fluids which indicated it is non pH dependant. The nucleus breadth is besides similar in both. HPMC besides was able to organize a gel bed nevertheless its size increased the slowest in both fluids when compared to the other polymers. It is non pH dependant. Again the nucleus was similar in both. Cellulose is really soluble and porous this could be why the gel bed was non really thick Methylcellulose ( MC ) was besides able to organize a gel bed and had similar consequences for both gel and nucleus breadth in both fluids. To reason Quick hydration and subsequent gel formation is a foremost and of import belongings of a polymer for it to be used for sustained release preparation. This is due to the thought that if the polymer does non hydrate rapidly, the surface barrier ( gel bed ) can non be formed instantly, which may do a big sum of drug to be released during the fast initial stage. Besides the thicker the bed the better this is because the more the matrix crestless waves, the longer the diffusion way length required for the drug to come out, which consequences in decreasing of release rate. Therefore all four tablets are acceptable to be used as hydrophilic matrices as they all form a gel bed but out of all four matrix tablets I believe XG to hold the best hydration features as it forms the quickest and thickest gel bed. There were a few restrictions. Cuting the tablets may hold affected the measuring of breadth, tabular arraies were hard to manage when nucleus was little and gel bed was big and finding the waterlessness of the nucleus was hard. Experiment A2: The purpose of experiment A2 was to see how different concentrations of polymer effected hydration of the matrix tablet. By and large the tendency shows that as you increase the concentration of polymer the rate of hydration lessenings. The consequences for the two fluids were similar nevertheless the hydration rate was somewhat greater in SGF. 5 % of polymer was excessively small to even organize a gel bed and therefore the tablet disintegrated directly off. At 10 % there was rapid formation of a gel bed nevertheless the nucleus breadth was low and the nucleus was wet bespeaking a high rate of drug release and the tablet disintegrated by 240mins. For 15, 20 and 30 % a gel bed did signifier at a slower rate severally but at that place was a higher nucleus breadth and the nucleus was drier. To reason, the greater the concentration of the polymer the thicker the gel bed. However it takes longer to organize. When the concentration of HPMC is low the gel bed is non thick and the hydrous matrix would be extremely porous with a low grade of tortuousness taking to low gel strength and rapid diffusion of the drug from matrix. Besides the addition in lactose at low concentrations of polymer agencies that it disintegrates faster. At high concentrations the matrix is more compact and the intermolecular interactions between the polymer means it is less porous so it takes longer to hydrate but when it does it organize a thick syrupy bed forestalling increased drug release. I believe at that place needs to be a via media between the rate of hydration and drug release. Therefore the best concentration to utilize would be about 20 % as it is able to organize a gel bed within 30mins and forestall a high rate of drug release. The restrictions for this experiment were similar to those fr om A1 Experiment A3: Experiment A3 involved the usage of the decomposition rigs. The thought of this trial was to see how polymer concentration effects hydration and decomposition of hydrophilic matrix tablets. The decomposition of three different concentrations ( 5, 15 and 30 % ) of SA, XG and HPMC were tested in SGF and SIF. For SA the general tendency showed that as polymer concentration increases the tablet disintegrates less. As discussed above in SGF SA forms an indissoluble polymer which makes it thicker than the bed in SIF. Therefore it would take longer for fluid to perforate the tablet in SGF and that is why it disintegrates quicker in SIF. In SIF it to the full disintegrates by 45mins for all concentrations but the tablet is still present in the SGF at this clip. For XG none of the tablets in both fluids managed to disintegrate. Disintegration was faster in SGF. This could be due to the sourness of the SGF. For SIF all three different concentration seemed to demo the same decomposition profile. As concentration increased in SGF the clip taken for decomposition increased like SA. For HPMC the consequences were surprising. For both the fluids all the concentrations of HPMC disintegrated wholly within the first hr and no gel bed was observed. Decomposition was faster in SIF. For SGF it took longer at higher concentrations. Therefore it did non demo sustained release belongingss like XG and SA. There were many restrictions. Exact clip of decomposition was difficult to find due to the clip intervals. Two different people were taking consequences so they would hold different subjective positions. Besides the graduated table used was obscure. The tablets could hold been assayed and more concentrations should hold been tested. Part B ( drug release ) : Part B was used to prove the drug release belongingss of hydrophilic matrix tablets. In order to make this the consequences obtained from the basket disintegration setup will be compared to the consequences from the flow rig setup. This will let us to find which disintegration method is more accurate every bit good as comparing their variableness. Revolving basket: If we look at the graph that shows the sum of drug released against clip. We can see that every bit shortly as the lactose tablet is inserted into the SIF there is an initial explosion of drug release. The sum of drug released continues to increase at a fast rate until around 30min where it begins to plateau and so lessening. The drug is released rapidly from the lactose tablet as there is no gel bed formed to decelerate the diffusion of drug out. Therefore the fluid rapidly disintegrates the milk sugar and all the drug is released. For the polymer tablet there is once more an initial explosion of drug release precisely the same as the lactose tablet. This is because the gel bed has non formed yet. Once the bed forms the sum of drug released begins to diminish compared to the control. It plateaus at around 15mins and so continues to let go of the same sum of drug for the remainder of the experiment. Therefore drug release continues for a longer period indicating sustained release. The rate of drug released for both the tablets start high and so bit by bit decreases. For the control the rate of release is ever greater than that of the polymer shown by the graph. For the control the drug is released quickly until there is none left. With the polymer it shows good modified release as the rate is a batch lower and is comparatively changeless between 5 to 15 mins. Flow -through rig: The flow rig showed clear conclusive consequences about the release profiles for the two different types of tablets. If we look at the graph demoing concentration of drug release over clip we can see directly off the modified release features of the polymer tablet. For the control every bit shortly as the rig is turned on we get immediate drug release. It continues to lift quickly until 10min and so begins to diminish until 60min where it is so wholly disintegrated. Both the tablets had disintegrated wholly. For the polymer we can once more see an initial explosion of drug release. This is because the gel bed has non formed. After 5 min one time the bed has formed the graph tableland and there is a changeless sum of drug released until 120min nevertheless the concentration of drug released is a batch lower than that of the control. When compared to the control there is a clear difference in the two release profiles. The two rigs both analysed the same thing but both had differing methods and gave different consequences. The basket method was simpler to put up and less fiddly to take consequences. However there were restrictions. Air bubbles on the basket could hold altered drug release, it was hard to reel the readings and during the start the clip intervals were really close together doing it difficult to take all the readings. The flow rig besides had drawbacks. First our setup 3 flow tubings were leaky. This meant that merchandise would hold been lost. Besides for one of the control rig the flow rig stopped working and no more consequences could be taken. Therefore we were unable to add mistake bars to the control graph. Finally merchandise may hold been lost when reassigning the pipes. Besides for both the experiments they did non mime the proper physiological conditions that would be present in the organic structure. If we compare the two methods I believe the flow-through rig gave more acc urate dependable consequences. The mistake bars were greater in the basket method significance at that place was a batch of fluctuation and the consequences would be hard to reproduce. Besides for the flow rig both groups showed indistinguishable consequences this was non the instance for basket. The flow rig showed the concentration of drug released at precisely the clip specified whereas the basket method shows the entire sum of drug released by the tablet at the specific clip so it is cumulative. Therefore the consequences for the flow rig are more good and manageable as the one graph gives all the needed information. Besides if the tubings were crystalline we could see the tablet. A reciprocating cylinder was besides used to prove drug release. Even though it mimics physiological conditions the best it provided inconclusive consequences in SIF for SGF it once more showed a lower rate of drug release for the polymer. However the mistake bars were really big for all the consequences and hence non accurate. Decision: By comparing the consequences from all the experiments we can reason Xanthan Gum is the best polymer to utilize for sustained release preparations, nevertheless all the polymers used produced acceptable hydrophilic matrices. XG had the most advantageous hydration profile compared to the other polymers as explained in the decision of portion A1. It can besides be seen that concentration of the polymer has an consequence on hydration explained in the decision of portion A2. XG showed sustained release at all concentrations but 15 % would be the best via media between decomposition clip and drug release. Finally drug release from tablets with polymers can clearly demo sustained release when tested by many different disintegration rigs nevertheless the flow-through rig proved to be the most successful.
Monday, March 2, 2020
McDonalds French Fries Are Still Not Vegetarian
McDonald's French Fries Are Still Not Vegetarian Most animal-rights activists follow a plant-based diet for ethical reasons and avoid places where billions of dead animals are served up every day. Still,à vegetarians or vegansà may be inclined to sneak into McDonalds on occasion for a serving of the famous Golden Arches french fries. If so, they should stop. In spite of numerous protests and even lawsuits, McDonalds french fries are not, and never have been, vegan or vegetarian. But how can that be? you might ask. French fries are made from potatoes and fried in oil, so theres no harm in grabbing a serving for the road. Right? Its All Good in India Sure. If you live in India. In that country, you can consume all the McDonalds French fries your heart desires because they are made of only plant-based ingredients. In fact, McDonalds in India does not serve pork or beef products at all. So if the fast-food giant can respect the fact that, in India, cows are sacred and not for consumption, as well as make veg-friendly fries, then why canââ¬â¢t they do it in the United States? Not in the U.S.A. However, French fries served at American McDonaldââ¬â¢s locations are not vegetarian. Thats because for decades McDonaldââ¬â¢s cooked its fries in beef fat- its supposedly what gave them their famous flavor. But when they switched to vegetable oil, the fries were no longer as tasty. The solution was to add natural beef flavor to the spuds. Class-Action Lawsuit In 2001, McDonaldââ¬â¢s was hit with a class-action lawsuit, led by a group of Hindu customers who felt they were being duped into unwittingly consuming animal products, which is strictly against their religion. Other vegetarians and vegans joined the fight, pointing out that the company gave out misleading information. Customers were being told that the French fries were fried in vegetable oil- the inference being that the fries were no longer cooked in lard and were therefore veg-friendly. Admitting that the fries were coated in beef flavoring, McDonalds settled for $10 million, with $6 million going to vegetarian organizations. Whats in a Fry? But they didnââ¬â¢t change their recipe one bit. Their website still lists the ingredients for all to see. As a representative explained: ââ¬Å"With regard to our French fries, any customer in the U.S. who contacts McDonalds USA to ask if they contain beef flavoring is told yes. The way it works is, McDonalds French fry suppliers add a very small amount of beef flavor to the oil in the par-frying process at the potato processing plant before shipping the spuds to individual outlets. Once at the restaurant, the fries are cooked in vegetable oil. That same representative went on to say that, In addition, we have no plans to change the way we prepare our French fries in the U.S. However, it is important to know that our French fries are prepared differently in other countries.â⬠To vegans and vegetarians, this is insulting. How difficult would it be to just leave out the beef flavoring like they do in India? The likely answer is that because the majority of customers in India are vegetarian or vegan, not accommodating their ethics would mean a loss of billions of dollars. Here in the United States, the opposite is likely to be true. Leave off the beef flavor that has long given the McDonalds French fry its famous flavor, and Americans are likely to just say no to Do you want fries with that?
Saturday, February 15, 2020
IT Development And Strategy Essay Example | Topics and Well Written Essays - 1250 words
IT Development And Strategy - Essay Example Describe ways of managing the transition in the support, turnaround, factory, and strategic quadrants? Transitions in the role of IT are crucial to enabling organizations to evolve in their reliance on IT for sustainable business processes. Various factors that are derived from within the environment or outside promote the assimilation of IT with business processes for greater efficiency, etc, thereby prompting the transformation in the role from support to turnaround to the factory and to strategic quadrant. Usually, these triggers are received from the environment and the changing trends in time, which also explains why several firms solely relying on IT for support services began incorporating IT to provide other services to their global consumers. A shift to the turnaround quadrant is often characterized by a need to identify IT as an opportunity in order to usefully utilize insightful data analytics to change strategies thereby gaining an advantage. Organizations that base heavi ly on their factory processes also find IT integration quite helpful in helping them optimize their uptimes. By doing so, they try to circumvent serious downtimes, of which even the slightest, costs a huge amount to any particular organizations (Applegate, Austin, Soule 2009, p. 427). That is why organizations use IT systems in order to prevent significant downtimes to keep their factory operations running smoothly and efficiently. This demonstrates a shift from turnaround to factory quadrant.
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